Generating facets for the independence system

In this paper, we present procedures to obtain facet-defining inequalities for the independence system polytope. These procedures are defined for inequalities which are not necessarily rank inequalities. We illustrate the use of these procedures by der iving strong valid inequalities for the acyclic induced subgraph, triangle free induced subgraph, bipartite induced subgraph, and knapsack polytopes. Finally, we derive a new family of facet-defining ineq ualities for the independence system polytope by adding a set of edges to antiwebs.© 2009 Society for Industrial and Applied Mathematics

Survivability in hierarchical telecommunications networks under dual homing

The motivation behind this study is the essential need for survivability in the telecommunications networks. An optical signal should find its destination even if the network experiences an occasional fiber cut. We consider the design of a two-level survivable telecommunications network. Terminals compiling the access layer communicate through hubs forming the backbone layer. To hedge against single link failures in the network, we require the backbone subgraph to be two-edge connected and the terminal nodes to connect to the backbone layer in a dual-homed fashion, i.e., at two distinct hubs. The underlying design problem partitions a given set of nodes into hubs and terminals, chooses a set of connections between the hubs such that the resulting backbone network is two-edge connected, and for each terminal chooses two hubs to provide the dual-homing backbone access. All of these decisions are jointly made based on some cost considerations. We give alternative formulations using cut inequalities, compare these formulations, provide a polyhedral analysis of the smallsized formulation, describe valid inequalities, study the associated separation problems, and design variable fixing rules. All of these findings are then utilized in devising an efficient branch-and-cut algorithm to solve this network design problem. © 2014 INFORMS

Survivability in hierarchical telecommunications networks

The survivable hierarchical telecommunications network design problem consists of locating concentrators, assigning user nodes to concentrators, and linking concentrators in a reliable backbone network. In this article, we study this problem when the backbone is 2-edge connected and when user nodes are linked to concentrators by a point-to-point access network. We formulate this problem as an integer linear program and present a facial study of the associated polytope. We describe valid inequalities and give sufficient conditions for these inequalities to be facet defining. We investigate the computational complexity of the corresponding separation problems. We propose some reduction operations to speed up the separation procedures. Finally, we devise a branch-and-cut algorithm based on these results and present the outcome of a computational study. © 2011 Wiley Periodicals, Inc

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

On the independent dominating set polytope

International audienc

Composition of Graphs and the Triangle-Free Subgraph Polytope

International audienc

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International audienc

Steiner trees and Polyhedra

this paper, we study polyhedra STP(G,S) and CON(G,S). We describe a new class of facet defining inequalities for the STP(G,S) that generalizes the families of constraints so called Steiner partition inequalities and odd hole inequalities introduced by Chopra and Rao [3]. We show that these inequalities may define facets for 2-trees, which invalidates a conjecture of Chopra and Rao [4]. We also discuss the closely related Steiner connected subgraph polytope. We describe some procedures of construction of facets from facets for CON(G,S). Using this, we obtain a complete description of both CON(G,S) and STP(G,S) for a special case of series-parallel graphs. Computational applications are also discussed. 2 Valid inequalitie